Thirty Years of Risk Assessments for Recombinant DNA Technology
نویسندگان
چکیده
Regulation of technologies using recombinant DNA (rDNA) methods and organisms has eased considerably over the past 30 years. Most of the previous risk assessments focused on the possibility of a recombinant organism or its genetic element establishing itself in the environment if it escaped from a laboratory or cell culture or fermentation facility. Since those assessments were conducted, deliberate releases of recombinant organisms have taken place in various agricultural field trials. This paper reviews the available risk assessments regarding rDNA in the environment and considers the possibility of horizontal gene transfer from eukaryotic cells, released via industrial cell culture or fermentation process waste streams, to prokaryotic cells in the environment.
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